Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212956 | 0.88 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9036795 | 0.87 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9440584 | 0.85 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9038104 | 0.85 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9049547 | 0.83 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9221207 | 0.83 | ALOX5 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9300222 | 0.82 | ALOX5 (0.51) | ALOX5PTGS1 | |
| SCHEMBL9440398 | 0.82 | ALOX5 (0.46) | ALOX5PTGS1 | |
| SCHEMBL9047329 | 0.82 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9037817 | 0.82 | ALOX5 (0.46) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453439-A | Antiinflammatory agent, antiallergen; lipoxygenase inhibitor | ZENECA LIMITED (GB) | 1995-09-26 | — | — | US | disclosed |