Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266439 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1TP53HSD17B10 | |
| SCHEMBL8608903 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1TP53HSD17B10 | |
| SCHEMBL13685294 | 0.77 | TET2 (0.31) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL9520079 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1TP53HSD17B10 | |
| SCHEMBL11670627 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1TP53HSD17B10 | |
| SCHEMBL1424635 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1TP53TSHR | |
| SCHEMBL15952106 | 0.72 | — | — | |
| SCHEMBL15952105 | 0.72 | — | — | |
| SCHEMBL11173637 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1TP53HSD17B10 | |
| SCHEMBL9422547 | 0.71 | ACACB (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455262-A | Treating arthritis, tumor metastasis, periodontal disease, corneal ulceration, bone resorption diseases, glomerular diseases | FLORIDA STATE UNIVERSITY (US) | 1995-10-03 | — | — | US | disclosed |