Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.49 |
| ▸ | CCKAR | P32238 | 9/20 | 0.49 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | BRD2 | P25440 | 3/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258549 | 1.00 | CCKBR (0.49) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL9258542 | 1.00 | CCKBR (0.49) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL9262954 | 0.87 | CCKBR (0.51) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL9262950 | 0.87 | CCKBR (0.51) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL9262943 | 0.87 | CCKBR (0.51) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL8235223 | 0.86 | BRD4 (0.63) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL9432720 | 0.85 | CCKBR (0.58) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL6939937 | 0.85 | CCKBR (0.58) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL6939944 | 0.85 | CCKBR (0.58) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL1574399 | 0.85 | CCKBR (0.65) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478933-A | Benzodiazepine derivatives and their use as antagonists of cholecystokinin and/or gastrin receptors | MERCK SHARPE & DOHME LTD. (GB) | 1995-12-26 | — | — | US | disclosed |
| WO-1993007131-A1 | BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF CHOLECYSTOKININ AND/OR GASTRIN RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |