Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258826 | 0.91 | — | — | |
| SCHEMBL11321265 | 0.88 | — | — | |
| SCHEMBL11337954 | 0.84 | — | — | |
| SCHEMBL11880786 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL11327246 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL291794 | 0.80 | — | — | |
| SCHEMBL13294284 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL3039505 | 0.78 | ALDH1A1 (0.41) | ALDH1A1THRB | |
| SCHEMBL5397047 | 0.77 | — | — | |
| SCHEMBL8458691 | 0.77 | ALDH1A1 (0.44) | ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457245-A | Protecting hydroxyl group of enantiomerically pure glycidol or 2-alkylglycidol, reductively cleaving with aromatic radical ion, reacting product with protected norcholanal derivative, deprotecting product, separating epimers | ALCON LABORATORIES, INC. (US) | 1995-10-10 | — | — | US | disclosed |
| US-5354872-A | Process for preparation of calcitriol lactone and related intermediates | ALCON LABORATORIES, INC. (US) | 1994-10-11 | — | — | US | disclosed |