Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 13/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.39 |
| ▸ | PRKCH | P24723 | 2/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622557 | 1.00 | PRKCA (0.50) | PRKCAPPARGTYRABHD16APTPN1 | |
| SCHEMBL9258666 | 1.00 | PRKCA (0.50) | PRKCAPPARGTYRABHD16APTPN1 | |
| SCHEMBL666234 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL9254632 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL664841 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL10186551 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL10186552 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL10186550 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL21182172 | 0.83 | PRKCA (0.51) | PRKCAPPARGTYRABHD16APRKD3 | |
| SCHEMBL9261402 | 0.83 | PRKCA (0.43) | PRKCAPPARGABHD16A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416224-A | Reaction of acetyldihydro-2-(3H)-furanone with aldehyde and alkali metal hydroxide | HENKEL CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0559789-A1 | PROCESS FOR THE PREPARATION OF $g(a)-ALKYL LACTONES | HENKEL CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5231192-A | Reacting an a-acyl lactone, an aldehyde and an alkali metal hydroxide; hydrogenation | HENKEL CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1992010487-A1 | PROCESS FOR CONVERTING α-ACYL-SUBSTITUTED LACTONES TO α-ALKYLIDENE-SUBSTITUTED LACTONES | HENKEL CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009590-A1 | PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES | HENKEL CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| US-4980342-A | Process for the preparation of α-alkyl lactones | HENKEL CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |