Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421065 | 0.91 | LMNA (0.59) | LMNAMMP9MMP8MMP13POLB | |
| SCHEMBL9259691 | 0.87 | LMNA (0.68) | RARBLMNAMMP9MMP8MMP13 | |
| SCHEMBL2412575 | 0.84 | LMNA (0.52) | LMNAMMP9MMP8MMP13POLB | |
| SCHEMBL8503477 | 0.83 | LMNA (0.57) | RARBLMNAMMP9MMP8MMP13 | |
| SCHEMBL9139904 | 0.81 | MAPK1 (0.59) | RARBLMNAMMP9MMP8MMP13 | |
| SCHEMBL8503491 | 0.81 | LMNA (0.57) | RARBLMNAMMP9MMP8MMP13 | |
| SCHEMBL8043388 | 0.79 | SMN1; SMN2 (0.57) | LMNAMMP9MMP8MMP13POLB | |
| SCHEMBL9476471 | 0.77 | SMN1; SMN2 (0.56) | RARBLMNAMMP9MMP8MMP13 | |
| SCHEMBL9478515 | 0.77 | KMT2A (0.59) | RARBLMNAMMP9MMP8MMP13 | |
| SCHEMBL10884235 | 0.77 | LMNA (0.49) | LMNAMMP9MMP8MMP13POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5417884-A | Containing a thiadiazole group | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-23 | — | — | US | disclosed |