Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28328475 | 0.93 | NPC1 (0.74) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL7343243 | 0.85 | NPC1 (0.77) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL16057079 | 0.83 | NPC1 (0.74) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL1538505 | 0.83 | RAB9A (0.79) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL29960037 | 0.83 | RAB9A (0.79) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL8956094 | 0.82 | NPC1 (0.72) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL28009686 | 0.82 | NPC1 (0.72) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL9642715 | 0.81 | NPC1 (0.89) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL28328478 | 0.81 | NPC1 (0.70) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL17197359 | 0.81 | NPC1 (0.70) | NPC1RAB9ARECQLKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501266-B1 | Bifunctional reactive dyes | BAYER AG (DE) | 1995-06-21 | — | — | EP | disclosed |
| US-5256774-A | Bifunctional reactive dyestuffs containing the 2-(N-substituted amino)-4-(N-phenylamino)-1,3,5-trlazinyl moiety | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0501266-A1 | Bifunctional reactive dyes | BAYER AG (DE) | 1992-09-02 | — | — | EP | disclosed |