Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257434 | 1.00 | NPC1 (0.42) | NPC1RAB9AF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL9256062 | 0.99 | NPC1 (0.41) | NPC1RAB9AF2F10PRSS1 | |
| SCHEMBL9251393 | 0.88 | ITGB3 (0.52) | NPC1RAB9AF2F10PRSS1 | |
| SCHEMBL9258269 | 0.88 | ITGB3 (0.52) | NPC1RAB9AF2F10PRSS1 | |
| SCHEMBL9254497 | 0.88 | F2 (0.38) | NPC1RAB9AF2F10PRSS1 | |
| SCHEMBL9253893 | 0.88 | F10 (0.40) | NPC1RAB9AF2F10PRSS1 | |
| SCHEMBL9257104 | 0.88 | HRH3 (0.39) | NPC1RAB9AHRH3HPGDTSHR | |
| SCHEMBL9248511 | 0.87 | HRH3 (0.42) | NPC1RAB9AHRH3HPGDTSHR | |
| SCHEMBL9251212 | 0.87 | HRH3 (0.42) | NPC1RAB9AHRH3HPGDTSHR | |
| SCHEMBL9257073 | 0.86 | F10 (0.39) | NPC1RAB9AF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | claimed |
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |