Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259095 | 1.00 | ALOX5 (0.45) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL9255381 | 0.86 | — | — | |
| SCHEMBL9255367 | 0.86 | — | — | |
| SCHEMBL9336376 | 0.78 | ALOX5 (0.47) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL9336383 | 0.78 | ALOX5 (0.47) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL9255127 | 0.75 | ALOX5 (0.37) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL9255131 | 0.75 | ALOX5 (0.37) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL9251531 | 0.74 | ALOX5 (0.50) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL9251543 | 0.74 | ALOX5 (0.50) | ALOX5TAS1R3TAS1R1GUSBPPARA | |
| SCHEMBL12518841 | 0.74 | ALOX5 (0.47) | ALOX5TAS1R3TAS1R1GUSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |