Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 9/20 | 0.62 |
| ▸ | HTR2C | P28335 | 7/20 | 0.61 |
| ▸ | HTR2B | P41595 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728227 | 0.87 | HTR2C (0.67) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1138149 | 0.82 | SLC5A2 (0.54) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL28440788 | 0.81 | MEN1 (0.53) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL25008617 | 0.81 | HTR2A (0.68) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL25008707 | 0.79 | HTR2A (0.66) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL26965662 | 0.79 | HTR2A (0.71) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL20898137 | 0.79 | HTR2C (0.65) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL8913458 | 0.79 | HTR2A (0.68) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL9664075 | 0.79 | HTR2C (0.75) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL26965675 | 0.79 | HTR2C (0.65) | MEN1KMT2AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455262-A | Treating arthritis, tumor metastasis, periodontal disease, corneal ulceration, bone resorption diseases, glomerular diseases | FLORIDA STATE UNIVERSITY (US) | 1995-10-03 | — | — | US | disclosed |