SCHEMBL8913458

SCHEMBL8913458

CCc1c[nH]c2cccc(O)c12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 10/20 0.68
HTR2C P28335 8/20 0.68
HTR2B P41595 7/20 0.68
GAA P10253 2/20 0.68
KDM4E B2RXH2 1/20 0.68
MEN1 O00255 1/20 0.68
ALDH1A1 P00352 1/20 0.68
POLB P06746 1/20 0.68
MAPT P10636 1/20 0.68
THRB P10828 1/20 0.68
DNMT1 P26358 1/20 0.68
RECQL P46063 1/20 0.68
CASP6 P55212 1/20 0.68
KMT2A Q03164 1/20 0.68
MCL1 Q07820 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
NPSR1 Q6W5P4 1/20 0.66
HTR1A P08908 2/20 0.65
DRD1 P21728 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27134372 0.86 HTR2A (0.71) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL26965700 0.83 HTR2A (0.71) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL26965688 0.83 HTR2A (0.63) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL26965662 0.82 HTR2A (0.71) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL26965675 0.81 HTR2C (0.65) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL20898137 0.81 HTR2C (0.65) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL9664075 0.81 HTR2C (0.75) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL7358453 0.81 ALDH1A1 (1.00) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL30681654 0.81 HTR2A (1.00) HTR2AHTR2CHTR2BGAAKDM4E
SCHEMBL19799204 0.81 GAA (0.62) HTR2AHTR2CHTR2BGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5609649-A Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them L'OREAL (FR) 1997-03-11 US claimed
EP-0428441-B1 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same OREAL (FR) 1994-08-24 EP claimed
CN-1051668-A Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out OREAL (FR) 1991-05-29 CN claimed
EP-0428441-A2 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same L'OREAL (FR) 1991-05-22 EP claimed
US-20230043896-A1 HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-02-09 US disclosed
US-10398145-B2 Kits comprising biopesticide compositions comprising myrosinase, glucosinolates and water soluble polyols MPT MUSTARD PRODUCTS & TECHNOLOGIES INC. (CA) 2019-09-03 US disclosed
US-20180000086-A1 Biopesticide Compositions Comprising Water Soluble Polyols Mustgrow Biologics Corp. (CA) 2018-01-04 US disclosed
US-9833000-B2 Biopesticide compositions comprising water soluble polyols MPT MUSTARD PRODUCTS & TECHNOLOGIES, INC. (CA) 2017-12-05 US disclosed
US-9833000-B2 Biopesticide compositions comprising water soluble polyols MPT MUSTARD PRODUCTS & TECHNOLOGIES, INC. (CA) 2017-12-05 US disclosed
US-20160113281-A1 Biopesticide Compositions Comprising Water Soluble Polyols Mustgrow Biologics Corp. (CA) 2016-04-28 US disclosed
US-20160113281-A1 Biopesticide Compositions Comprising Water Soluble Polyols Mustgrow Biologics Corp. (CA) 2016-04-28 US disclosed
US-9258999-B2 Biopesticide compositions comprising water soluble polyols MPT MUSTARD PRODUCTS & TECHNOLOGIES, INC. (CA) 2016-02-16 US disclosed
US-9258999-B2 Biopesticide compositions comprising water soluble polyols MPT MUSTARD PRODUCTS & TECHNOLOGIES, INC. (CA) 2016-02-16 US disclosed
US-20150037310-A1 Biopesticide Compositions Comprising Water Soluble Polyols Mustgrow Biologics Corp. (CA) 2015-02-05 US disclosed
US-20150037310-A1 Biopesticide Compositions Comprising Water Soluble Polyols Mustgrow Biologics Corp. (CA) 2015-02-05 US disclosed
US-5609649-A Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them L'OREAL (FR) 1997-03-11 US disclosed
EP-0428441-B1 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same OREAL (FR) 1994-08-24 EP disclosed
CN-1051668-A Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out OREAL (FR) 1991-05-29 CN disclosed
EP-0428441-A2 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same L'OREAL (FR) 1991-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10398145-B2 Kits comprising biopesticide compositions comprising myrosinase, glucosinolates and water soluble polyols MGAM, AGL, MGLL HTR2A 4753/4885HTR2C 4530/4885HTR2B 4786/4885
US-20180000086-A1 Biopesticide Compositions Comprising Water Soluble Polyols MGAM, MGAM2, AGL HTR2A 4693/4885HTR2C 4667/4885HTR2B 4823/4885
US-20160113281-A1 Biopesticide Compositions Comprising Water Soluble Polyols MGAM, MGAM2, AGL HTR2A 4693/4885HTR2C 4667/4885HTR2B 4823/4885
US-20230043896-A1 HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING HTR1B, HTR2B, CYP8B1 HTR2A 24/4885HTR2C 6/4885HTR2B 2/4885
US-20150037310-A1 Biopesticide Compositions Comprising Water Soluble Polyols MGAM, MGAM2, AGL HTR2A 4693/4885HTR2C 4667/4885HTR2B 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.