SCHEMBL9259185

SCHEMBL9259185

C=CCOC(=O)N1C[C@@H](S)C[C@H]1C=C(Cl)CNS(C)(=O)=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.31
DPP4 P27487 1/20 0.31
PREP P48147 1/20 0.31
FAP Q12884 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9259181 1.00 SIGMAR1 (0.31) SIGMAR1DPP4PREPFAP
SCHEMBL9271968 0.89 SIGMAR1 (0.31) SIGMAR1DPP4PREPFAP
SCHEMBL9271972 0.89 SIGMAR1 (0.31) SIGMAR1DPP4PREPFAP
SCHEMBL9268368 0.82 SIGMAR1 (0.31) SIGMAR1
SCHEMBL9272189 0.82 SIGMAR1 (0.31) SIGMAR1
SCHEMBL9268364 0.82 SIGMAR1 (0.31) SIGMAR1
SCHEMBL9283457 0.78
SCHEMBL9283449 0.78
SCHEMBL9258361 0.77 CYP19A1 (0.30)
SCHEMBL9272907 0.77 SIGMAR1 (0.31) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995014692-A1 CABAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME DONG-A PHARMACEUTICAL CO., LTD. (KR) 1995-06-01 WO disclosed