Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284183 | 0.87 | MAPT (0.51) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL8953170 | 0.83 | NPSR1 (0.70) | ALDH1A1HTR1AHPGDPOLBCA12 | |
| SCHEMBL280240 | 0.78 | MEN1 (0.76) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL6569882 | 0.76 | CD274 (0.77) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL4488493 | 0.76 | CD274 (0.77) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL22015906 | 0.76 | HDAC1 (0.71) | ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL14139926 | 0.75 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL8404677 | 0.75 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL11478379 | 0.75 | CD274 (0.71) | CD274ALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL8244325 | 0.75 | CD274 (0.67) | CD274ALDH1A1HTR1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5427774-A | A cationic sunscreen agents; water insolubility, receptivity, nonhydrolyzing, chemical resistance, stability | ISP VAN DYK INC. (US) | 1995-06-27 | — | — | US | disclosed |