Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259369 | 0.87 | CD274 (0.60) | HPGDCYP2C19ALDH1A1CD274HTR1A | |
| SCHEMBL13492542 | 0.76 | KMT2A (0.71) | TP53LMNAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL14864329 | 0.73 | ALDH1A1 (0.74) | MAPTLMNAKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12090046 | 0.73 | LMNA (0.58) | TP53LMNAKMT2AHPGDNPC1 | |
| SCHEMBL2228237 | 0.73 | ALDH1A1 (0.66) | MAPTKMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL22015906 | 0.71 | HDAC1 (0.71) | MAPTKMT2AHPGDNPC1HDAC1 | |
| SCHEMBL8953170 | 0.71 | NPSR1 (0.70) | KMT2AHPGDHDAC1HDAC10HDAC6 | |
| SCHEMBL1665580 | 0.70 | SMN1; SMN2 (0.64) | MAPTTP53LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL13753321 | 0.70 | ALDH1A1 (0.61) | MAPTLMNAKMT2ASMN1; SMN2HPGD | |
| SCHEMBL12132533 | 0.68 | LMNA (0.64) | MAPTLMNAKMT2ASMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5427774-A | A cationic sunscreen agents; water insolubility, receptivity, nonhydrolyzing, chemical resistance, stability | ISP VAN DYK INC. (US) | 1995-06-27 | — | — | US | disclosed |