Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861455 | 0.94 | KCNA5 (0.46) | KCNA5CYP11B2CYP11B1KCNN4HTT | |
| SCHEMBL9276050 | 0.82 | KMT2A (0.43) | KCNA5CYP11B2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL5516786 | 0.81 | ALDH1A1 (0.42) | HTTTSHRPOLBMAPTMAPK1 | |
| SCHEMBL43388 | 0.81 | ALDH1A1 (0.42) | HTTTSHRPOLBMAPTMAPK1 | |
| SCHEMBL18560654 | 0.81 | KCNA5 (0.46) | KCNA5CYP11B2CYP11B1KCNN4HTT | |
| SCHEMBL28847835 | 0.78 | KCNA5 (0.46) | KCNA5CYP11B2CYP11B1KCNN4HTT | |
| SCHEMBL8504493 | 0.74 | KCNA5 (0.43) | KCNA5KCNN4HTTGAAMAPT | |
| SCHEMBL10985893 | 0.74 | KCNA5 (0.43) | KCNA5CYP11B2CYP11B1KCNN4HTT | |
| SCHEMBL2646034 | 0.74 | KCNA5 (0.43) | KCNA5CYP11B2CYP11B1KCNN4HTT | |
| Hydrochloric Acid SCHEMBL27850698 | 0.73 | KCNA5 (0.42) | KCNA5CYP11B2CYP11B1KCNN4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |