Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.53 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | RARG | P13631 | 4/20 | 0.41 |
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259752 | 1.00 | PLA2G4A (0.53) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL9259750 | 1.00 | PLA2G4A (0.53) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL8795740 | 1.00 | PLA2G4A (0.53) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL9259755 | 1.00 | PLA2G4A (0.53) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL8796110 | 0.90 | PLA2G4A (0.46) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL8796204 | 0.89 | PLA2G4A (0.48) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL8796190 | 0.89 | PLA2G4A (0.48) | PLA2G4ARARBRARGRARAMAOB | |
| SCHEMBL8795228 | 0.86 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARACYP26A1 | |
| SCHEMBL9254004 | 0.86 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARACYP26A1 | |
| SCHEMBL9254001 | 0.86 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | claimed |
| EP-0629604-A2 | Alicyclic phospholipase A2 inhibitors | Bristol-Myers Company (US) | 1994-12-21 | — | — | EP | claimed |
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0629604-A2 | Alicyclic phospholipase A2 inhibitors | Bristol-Myers Company (US) | 1994-12-21 | — | — | EP | disclosed |