Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 14/20 | 0.48 |
| ▸ | PPARA | Q07869 | 14/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263906 | 0.88 | PPARG (0.55) | FFAR1PPARGPPARAPOLBMAPT | |
| SCHEMBL9259822 | 0.88 | FFAR1 (0.52) | FFAR1PPARGPPARAPOLBMAPT | |
| SCHEMBL9258855 | 0.85 | FFAR1 (0.67) | FFAR1PPARGPPARA | |
| SCHEMBL9259825 | 0.83 | PPARG (0.53) | FFAR1PPARGPPARAPOLBMAPT | |
| SCHEMBL9005899 | 0.80 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL9005900 | 0.79 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL9253284 | 0.79 | PPARG (0.55) | FFAR1PPARGPPARAPOLBMAPT | |
| SCHEMBL9156966 | 0.78 | PPARA (0.61) | PPARGPPARA | |
| SCHEMBL9176979 | 0.78 | PPARG (0.66) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL9005933 | 0.78 | PPARG (0.54) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | claimed |
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |