Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45332 | 0.82 | AKT1 (0.48) | MAPTLMNACA1CA2CA12 | |
| Hydroxylated Completely Delakylated Diethylpropion SCHEMBL27460979 | 0.72 | CA1 (0.50) | PDPK1MAPTLMNAHTTESR1 | |
| Hydroxylated Completely Delakylated Diethylpropion SCHEMBL5319402 | 0.72 | CA1 (0.50) | PDPK1MAPTLMNAHTTESR1 | |
| SCHEMBL1223467 | 0.71 | CA1 (0.50) | PDPK1MAPTLMNAHTTESR1 | |
| Hydroxylated Completely Delakylated Diethylpropion SCHEMBL5172799 | 0.71 | CA1 (0.48) | PDPK1MAPTLMNAHTTESR1 | |
| SCHEMBL9658758 | 0.69 | CA1 (0.47) | PDPK1MAPTLMNAHTTESR1 | |
| SCHEMBL11538990 | 0.68 | PDPK1 (0.50) | ALDH5A1ABATPDPK1MAPTLMNA | |
| SCHEMBL6654144 | 0.68 | PDPK1 (0.46) | PDPK1MAPTLMNAHTTESR1 | |
| SCHEMBL6654142 | 0.68 | PDPK1 (0.46) | PDPK1MAPTLMNAHTTESR1 | |
| SCHEMBL2574988 | 0.68 | PDPK1 (0.46) | PDPK1MAPTLMNAHTTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431871-B1 | A process for the preparation of ketones | FINE ORGANICS LTD (GB) | 1995-06-07 | — | — | EP | claimed |
| US-5276191-A | Reacting phenol with a nitrile in presence of Lewis acid catalyst in nitroalkane solvent to produce aminoalkyl para-hydroxyphenyl ketone | FINE ORGANICS LIMITED (GB) | 1994-01-04 | — | — | US | claimed |
| EP-0431871-A2 | A process for the preparation of ketones | FINE ORGANICS LIMITED (GB) | 1991-06-12 | — | — | EP | claimed |
| JP-3279351-A | — | — | None | — | — | JP | disclosed |
| EP-0431871-B1 | A process for the preparation of ketones | FINE ORGANICS LTD (GB) | 1995-06-07 | — | — | EP | disclosed |
| US-5276191-A | Reacting phenol with a nitrile in presence of Lewis acid catalyst in nitroalkane solvent to produce aminoalkyl para-hydroxyphenyl ketone | FINE ORGANICS LIMITED (GB) | 1994-01-04 | — | — | US | disclosed |
| US-5276191-A | Reacting phenol with a nitrile in presence of Lewis acid catalyst in nitroalkane solvent to produce aminoalkyl para-hydroxyphenyl ketone | FINE ORGANICS LIMITED (GB) | 1994-01-04 | — | — | US | disclosed |
| JP-H03279351-A | PREPARATION OF KETONE | FINE ORGANICS LTD | 1991-12-10 | — | — | JP | disclosed |
| EP-0431871-A2 | A process for the preparation of ketones | FINE ORGANICS LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0431871-A2 | A process for the preparation of ketones | FINE ORGANICS LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |