SCHEMBL45332

SCHEMBL45332

C=CC(N)C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.48
LMNA P02545 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
TSHR P16473 2/20 0.43
MAPT P10636 2/20 0.43
CYP3A4 P08684 2/20 0.43
POLB P06746 1/20 0.43
PARP1 P09874 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MDM2 Q00987 1/20 0.42
ALDH1A1 P00352 3/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL28791587 0.91 LMNA (0.45) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL9259986 0.82 ALDH5A1 (0.50) LMNACES2MAPTCYP3A4BLM
SCHEMBL13180625 0.81 TDP1 (0.48) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL932126 0.80 TDP1 (0.52) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL11036479 0.79 MAPT (0.56) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL1720153 0.78 AKT1 (0.52) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL11287380 0.78 LMNA (0.54) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL45241 0.77 LMNA (0.52) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL28194072 0.76 AKT1 (0.50) AKT1LMNATDP1L3MBTL1CES2
SCHEMBL9093296 0.75 LMNA (0.51) AKT1LMNATDP1L3MBTL1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115943081-A Fast actinically curable composition for 3D composites 法国阿科玛 2023-04-07 CN claimed
CN-115708016-A Photosensitive resin composition, photocured product of the composition, and printed wiring board having photocured film of the composition 株式会社田村制作所 2023-02-21 CN claimed
CN-114479649-A Corrosion-resistant material, terminal-equipped electric wire, and wire harness 矢崎总业株式会社 2022-05-13 CN claimed
CN-110095938-A Photosensitive polymer combination 株式会社田村制作所 2019-08-06 CN claimed
CN-109535284-A Photoinitiator composite suitable for UV-LED light radiation and the water-based paint compositions by its preparation 广东华润涂料有限公司 2019-03-29 CN claimed
CN-109071694-A Ultraviolet-curing resin composition, solidification envelope and laminated body 横滨橡胶株式会社 2018-12-21 CN claimed
EP-2850112-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP claimed
EP-2850111-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP claimed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US claimed
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers COLOPLAST A/S (DK) 2018-08-07 US claimed
WO-2011160639-A1 SKIN-FRIENDLY ADHESIVES FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
WO-2011160638-A1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
WO-2011160637-A2 POLYURETHANE BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO claimed
WO-2011103878-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2011-09-01 WO claimed
CN-101878191-A Preparation method of copolymerizable photoinitiators AGFA GRAPHICS NV 2010-11-03 CN claimed
CN-101835857-A Radiation curable inkjet fluids and inks improved for photoyellowing AGFA GRAPHICS NV 2010-09-15 CN claimed
CN-101503588-A Energy ray-curable ink composition HITACHI MAXELL (JP) 2009-08-12 CN claimed
CN-101466805-A UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG (DE) 2009-06-24 CN claimed
EP-0210904-B1 PHENYL-(3-HEXAMETHYLENE IMINOPROPYL) KETONE, PROCESS FOR ITS PREPARATION AND THERAPEUTICAL USE LABORATOIRE L. LAFON Société anonyme dite: (FR) 1989-09-06 EP claimed
US-4758560-A Phenyl-(3-hexamethyleneiminopropyl)-ketone SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1988-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers ACMSD, AAAS, PPOX AKT1 3314/4885LMNA 2961/4885TDP1 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.