SCHEMBL9260

SCHEMBL9260

O=[C]OCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.55
TSHR P16473 1/20 0.55
HPGD P15428 1/20 0.54
HTT P42858 1/20 0.54
MAOB P27338 1/20 0.49
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
RECQL P46063 1/20 0.44
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ACHE P22303 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2074834 0.87 ALDH1A1 (0.56) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL10860882 0.85 TSHR (0.46) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL28312039 0.85 ALDH1A1 (0.48) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL1967926 0.84 ALDH1A1 (0.53) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL28411579 0.81 ALDH1A1 (0.50) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL20590968 0.81 ALDH1A1 (0.50) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL77922 0.81 ALDH1A1 (0.62) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL5067946 0.80 TDP1 (0.45) ALDH1A1TSHRHPGDHTTNPC1
SCHEMBL9315193 0.79 ALDH1A1 (0.51) ALDH1A1TSHRHPGDHTTMAOB
SCHEMBL3937020 0.79 ALDH1A1 (0.55) ALDH1A1TSHRHPGDHTTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11891668-B2 Methods for generating therapeutic delivery platforms THE UNIVERSITY OF KANSAS (US) 2024-02-06 US claimed
CN-113929748-B Kit for detecting BACE1 enzyme activity and application thereof 中国科学技术大学 2023-10-20 CN claimed
CN-116854907-A Polypeptide and nano-assembly and preparation method thereof 中国科学技术大学 2023-10-10 CN claimed
CN-116396296-A Preparation method of ertapenem 武汉瑞晟药业有限公司 2023-07-07 CN claimed
US-20230113948-A1 SYNTHETIC PROCESSES AND INTERMEDIATES ARBUTUS BIOPHARMA CORPORATION (US) 2023-04-13 US claimed
WO-2023049774-A1 GENETICALLY ENCODED AND EXOGENOUSLY TRIGGERED PROTEIN-PROTEIN LIGATION UNIVERSITY OF WASHINGTON (US) 2023-03-30 WO claimed
EP-4140988-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2023-03-01 EP claimed
CN-114846051-A Synthetic methods and intermediates 阿布特斯生物制药公司 2022-08-02 CN claimed
US-11235330-B2 Hydrogel membrane and methods for selective retrieval of microbial targets KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-02-01 US claimed
CN-113929748-A Kit for detecting activity of BACE1 enzyme and application 中国科学技术大学 2022-01-14 CN claimed
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US claimed
US-4272432-A Claudogenic-interceptive nonapeptide AMERICAN HOME PRODUCTS CORPORATION (US) 1981-06-09 US claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-4180571-A Arylmalonamido-1-oxadethiacephalosporins SHIONOGI & CO., LTD. (JP) 1979-12-25 US claimed
US-4146633-A ANTIBIOTICS, BACTERICIDES MERCK & CO., INC. (US) 1979-03-27 US claimed
US-4081433-A D-Nle4 -somatostatin and analogues thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1978-03-28 US claimed
US-4061608-A POLYPEPTIDE, INHIBIT SECRETION OF GROWTH HORMONE AMERICAN HOME PRODUCTS CORPORATION (US) 1977-12-06 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3998795-A (Acyl-D-α-amino acid-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-21 US claimed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed