SCHEMBL9260320

SCHEMBL9260320

NOCC(F)=Cc1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.39
AGXT P21549 2/20 0.39
GRIK1 P39086 1/20 0.37
TRPA1 O75762 1/20 0.37
FBP1 P09467 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
MAOB P27338 2/20 0.35
HSD17B10 Q99714 1/20 0.34
TDO2 P48775 1/20 0.34
GRIN2D O15399 2/20 0.34
GRIN3B O60391 2/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2A Q12879 2/20 0.34
GRIN2B Q13224 2/20 0.34
GRIN2C Q14957 2/20 0.34
GRIN3A Q8TCU5 2/20 0.34
CYP2C9 P11712 1/20 0.34
PTGS2 P35354 1/20 0.34
AOC3 Q16853 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9260318 1.00 IDO1 (0.39) IDO1AGXTGRIK1TRPA1FBP1
SCHEMBL1689623 0.76 TRPA1 (0.41) GRIK1TRPA1FBP1ALDH1A1HTT
SCHEMBL1689621 0.76 TRPA1 (0.41) GRIK1TRPA1FBP1ALDH1A1HTT
SCHEMBL1689625 0.76 TRPA1 (0.41) GRIK1TRPA1FBP1ALDH1A1HTT
SCHEMBL1689703 0.75 TRPA1 (0.44) GRIK1TRPA1FBP1ALDH1A1HTT
SCHEMBL1689704 0.75 TRPA1 (0.44) GRIK1TRPA1FBP1ALDH1A1HTT
SCHEMBL29043108 0.71 TRPA1 (0.47) TRPA1FBP1ALDH1A1HTTMAOB
SCHEMBL9261731 0.67 MAOB (0.39) IDO1ALDH1A1MAOBCYP2C9AOC3
SCHEMBL18345499 0.64 HSD17B10 (0.50) GRIK1TRPA1FBP1ALDH1A1HTT
SCHEMBL18345496 0.64 HSD17B10 (0.50) GRIK1TRPA1FBP1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5462961-A Insecticides, acaricides, fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-10-31 US disclosed
EP-0390498-B1 A heterocyclic compound, production of same and use SUMITOMO CHEMICAL CO (JP) 1994-07-27 EP disclosed
EP-0390498-A1 A heterocyclic compound, production of same and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-03 EP disclosed