Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697763 | 0.91 | EPHX1 (0.69) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803830 | 0.87 | EPHX1 (0.97) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9258583 | 0.87 | EPHX1 (0.76) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL5146715 | 0.86 | EPHX1 (1.00) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803307 | 0.86 | EPHX1 (1.00) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803313 | 0.86 | EPHX1 (1.00) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL14288522 | 0.86 | EPHX1 (0.90) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9705544 | 0.83 | EPHX1 (0.69) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9261957 | 0.82 | EGFR (0.60) | EPHX1NPC1RAB9AMAPTEGFR | |
| SCHEMBL22803696 | 0.80 | NPC1 (0.67) | EPHX1NPC1RAB9AMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418237-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-05-23 | — | — | US | disclosed |