Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260337 | 0.91 | EPHX1 (0.76) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9705544 | 0.86 | EPHX1 (0.69) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL14288522 | 0.84 | EPHX1 (0.90) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803696 | 0.83 | NPC1 (0.67) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL9258583 | 0.83 | EPHX1 (0.76) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803830 | 0.83 | EPHX1 (0.97) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803823 | 0.83 | EPHX1 (0.68) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL1948423 | 0.82 | MAOB (0.64) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL31668688 | 0.82 | MAOA (0.66) | EPHX1NPC1RAB9AMAPTMAOB | |
| SCHEMBL22803307 | 0.82 | EPHX1 (1.00) | EPHX1NPC1RAB9AMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| US-5530026-A | WITHOUT SYSTEMIC TOXICITY AND MUTAGENICITY | UNIVERSITE LAVAL (CA) | 1996-06-25 | — | — | US | disclosed |