Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255906 | 0.95 | ACHE (0.50) | ACHEBCHEAPPHTTGAA | |
| SCHEMBL9259427 | 0.84 | ACHE (0.49) | ACHEBCHEAPPGAAPOLB | |
| SCHEMBL9252813 | 0.81 | ACHE (0.64) | ACHEBCHEAPPTSHR | |
| SCHEMBL9261779 | 0.81 | ACHE (0.48) | ACHEBCHEAPPTSHRKMT2A | |
| SCHEMBL9250740 | 0.80 | ACHE (0.53) | ACHEBCHEAPPHTTGAA | |
| SCHEMBL9257198 | 0.80 | ACHE (0.47) | ACHEBCHEAPPKMT2A | |
| SCHEMBL9261162 | 0.79 | ACHE (0.65) | ACHEBCHEAPPTSHR | |
| SCHEMBL8472225 | 0.79 | HTT (0.71) | ACHEBCHEHTTGAAMAPT | |
| SCHEMBL9261276 | 0.79 | ACHE (0.68) | ACHEHTTGAAMAPTPOLB | |
| SCHEMBL9257365 | 0.77 | ACHE (0.61) | ACHEBCHEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |