Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738781 | 1.00 | MAPT (0.51) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL4771965 | 0.98 | MAPT (0.49) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL4010761 | 0.88 | L3MBTL1 (0.51) | MAPTMEN1LMNASLC6A3KMT2A | |
| SCHEMBL4706175 | 0.87 | L3MBTL1 (0.50) | MAPTMEN1LMNASLC6A3KMT2A | |
| SCHEMBL28158323 | 0.85 | KDM4E (0.58) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933764 | 0.84 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL9992785 | 0.84 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL14339056 | 0.84 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933728 | 0.84 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933962 | 0.84 | L3MBTL1 (0.65) | MAPTMEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |