Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257804 | 0.82 | PIK3CD (0.35) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7176893 | 0.79 | TLR7 (0.37) | TLR7L3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL179319 | 0.76 | CCR4 (0.39) | TLR7L3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29670237 | 0.73 | SLC6A3 (0.34) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL22824973 | 0.72 | SLC6A3 (0.35) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8881509 | 0.71 | APEX1 (0.34) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9255061 | 0.71 | SLC6A3 (0.35) | SLC6A3 | |
| SCHEMBL19387943 | 0.71 | SLC6A3 (0.34) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20780330 | 0.71 | CCR4 (0.36) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20738457 | 0.71 | SLC6A3 (0.34) | TLR7PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457205-A | Substituted thiazoles useful for treatment of diabetes | DR. KARL THOMAE GMBH (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |
| US-4886814-A | LOWER BLOOD SUGAR | DR. KARL THOMAS GMBH (DE) | 1989-12-12 | — | — | US | disclosed |