Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.76 |
| ▸ | ATP4B | P51164 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272822 | 0.92 | ATP4A (0.64) | ATP4AATP4B | |
| SCHEMBL9650832 | 0.92 | ATP4A (0.80) | ATP4AATP4B | |
| SCHEMBL9723909 | 0.88 | ATP4A (0.74) | ATP4AATP4B | |
| SCHEMBL9270832 | 0.88 | ATP4A (0.74) | ATP4AATP4B | |
| SCHEMBL9349742 | 0.88 | ATP4A (0.74) | ATP4AATP4B | |
| SCHEMBL9723915 | 0.87 | ATP4A (0.73) | ATP4AATP4B | |
| SCHEMBL9271880 | 0.86 | — | — | |
| SCHEMBL9723912 | 0.86 | ATP4A (0.74) | ATP4AATP4B | |
| SCHEMBL9272700 | 0.86 | ATP4A (0.71) | ATP4AATP4B | |
| SCHEMBL9723910 | 0.86 | ATP4A (0.78) | ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432182-A | Inhibitors of gastric acid secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-07-11 | — | — | US | disclosed |
| EP-0416749-B1 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT (NL) | 1994-08-17 | — | — | EP | disclosed |
| EP-0330485-B1 | 4-AMINO-3-ACYL QUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | SmithKline Beecham Intercredit B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |
| US-5082841-A | Enzyme inhibitor | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1992-01-21 | — | — | US | disclosed |
| EP-0416749-A2 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989008104-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |
| EP-0330485-A1 | 4-Amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion | SmithKline Beecham Intercredit B.V. (NL) | 1989-08-30 | — | — | EP | disclosed |