Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745723 | 0.87 | MAOB (0.46) | SLC6A2MAPK1LMNA | |
| SCHEMBL6644617 | 0.77 | SLC6A2 (0.48) | HRH1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL5572358 | 0.71 | MAOB (0.46) | SLC6A2MAPK1LMNA | |
| SCHEMBL26965306 | 0.70 | TAAR1 (0.43) | KMT2AMAPK1 | |
| SCHEMBL8867124 | 0.69 | SLC6A2 (0.60) | HRH1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL3836889 | 0.69 | KMT2A (0.53) | HRH1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL28654764 | 0.69 | SLC6A2 (0.46) | HRH1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL4066883 | 0.69 | KMT2A (0.48) | SLC6A2SLC6A4SLC6A3KMT2AHTT | |
| SCHEMBL10398183 | 0.69 | TAAR1 (0.41) | KMT2AHTTMAPK1 | |
| SCHEMBL25039218 | 0.68 | KMT2A (0.52) | SLC6A2SLC6A4SLC6A3KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446051-A | Nervous system disorder and brain disorder | ELI LILLY AND COMPANY (US) | 1995-08-29 | — | — | US | disclosed |