Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003017 | 0.91 | KMT2A (0.56) | KMT2AMEN1CYP19A1TSHRCYP1A2 | |
| SCHEMBL240161 | 0.85 | MAPK1 (0.50) | KMT2ATSHRCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL10838797 | 0.81 | CYP19A1 (0.64) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL25039218 | 0.81 | KMT2A (0.52) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL9317593 | 0.81 | ESR1 (0.60) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL9906175 | 0.77 | KMT2A (0.82) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL16144309 | 0.77 | KMT2A (0.82) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL11188153 | 0.77 | KIF11 (0.48) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL4062666 | 0.77 | KMT2A (0.82) | KMT2AMEN1CYP19A1KIF11TSHR | |
| SCHEMBL27313443 | 0.77 | HDAC3 (0.50) | KMT2AMEN1CYP19A1KIF11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094457-A2 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS (US) | 2009-07-30 | — | — | WO | disclosed |