Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263676 | 0.92 | SLC2A1 (0.53) | SLC2A1PTGS2SLC11A2KIF11DAO | |
| SCHEMBL9268107 | 0.88 | SLC2A1 (0.57) | SLC2A1CHEK2MMP14KIF11MMP2 | |
| SCHEMBL9266242 | 0.87 | SLC2A1 (0.51) | SLC2A1PTGS2KIF11MMP2MMP9 | |
| SCHEMBL9268714 | 0.85 | SLC2A1 (0.55) | SLC2A1PTGS2 | |
| SCHEMBL9268964 | 0.84 | SLC2A1 (0.58) | SLC2A1PTGS2SLC11A2CHEK2MMP14 | |
| SCHEMBL9272554 | 0.83 | SLC2A1 (0.56) | SLC2A1MMP2MMP9 | |
| SCHEMBL9261054 | 0.82 | SLC2A1 (0.74) | SLC2A1PTGS2 | |
| SCHEMBL9261485 | 0.81 | SLC2A1 (0.46) | SLC2A1PTGS2 | |
| SCHEMBL9263700 | 0.79 | BRD4 (0.49) | SLC2A1PTGS2SLC11A2 | |
| SCHEMBL4472787 | 0.79 | SLC2A1 (0.58) | SLC2A1SLC11A2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | claimed |
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |