Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260928 | 0.88 | SLC2A1 (0.51) | SLC2A1KIF11CHEK2MMP2MMP9 | |
| SCHEMBL9261485 | 0.86 | SLC2A1 (0.46) | SLC2A1SCN9ANR1H2NR1H3 | |
| SCHEMBL4469241 | 0.86 | SLC2A1 (0.51) | SLC2A1KIF11CHEK2KDM4EALDH1A1 | |
| SCHEMBL9272554 | 0.83 | SLC2A1 (0.56) | SLC2A1LMNANPSR1BRD4MMP2 | |
| SCHEMBL9266242 | 0.81 | SLC2A1 (0.51) | SLC2A1KIF11SCN9AMMP2MMP9 | |
| SCHEMBL9263676 | 0.80 | SLC2A1 (0.53) | SLC2A1KIF11 | |
| SCHEMBL3560834 | 0.80 | SLC2A1 (0.44) | SLC2A1KIF11CHEK2KDM4EALDH1A1 | |
| SCHEMBL19047179 | 0.80 | BRD4 (0.45) | SLC2A1KIF11CHEK2KDM4EALDH1A1 | |
| SCHEMBL9268714 | 0.79 | SLC2A1 (0.55) | SLC2A1SCN9A | |
| SCHEMBL9264396 | 0.78 | SLC2A1 (0.57) | SLC2A1KDM4EBRD4NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |