Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265685 | 0.89 | SLC2A1 (0.62) | SLC2A1MAPK1HPGDBRD4MAPT | |
| SCHEMBL9264323 | 0.88 | SLC2A1 (0.60) | SLC2A1MAPK1HPGDBRD4MAPT | |
| SCHEMBL9271041 | 0.86 | SLC2A1 (0.50) | SLC2A1SRD5A2MAPK1HPGDCNR1 | |
| SCHEMBL9270359 | 0.81 | SLC2A1 (0.78) | SLC2A1NPSR1BRD4MAPTCHEK2 | |
| SCHEMBL9282992 | 0.79 | SLC2A1 (0.52) | SLC2A1MAPK1HPGDBRD4GAA | |
| SCHEMBL3392710 | 0.76 | SLC2A1 (0.48) | SLC2A1HPGDBRD4MAPTGAA | |
| SCHEMBL3392595 | 0.76 | SLC2A1 (0.48) | SLC2A1MAPK1HPGDBRD4MAPT | |
| SCHEMBL9272305 | 0.76 | PDGFRA (0.50) | SLC2A1BRD4MAPTGAAMEN1 | |
| SCHEMBL9266330 | 0.75 | TYMP (0.50) | SLC2A1GAAMEN1KMT2A | |
| SCHEMBL4478739 | 0.74 | SLC2A1 (0.47) | SLC2A1MAPK1CNR2BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |