Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12905164 | 0.85 | PDK2 (0.31) | PDK2ORAI1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL925878 | 0.85 | PDK2 (0.39) | PDK2ORAI1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL926057 | 0.82 | EPHX2 (0.35) | PDK2L3MBTL1EPHX2NR1H4MAPT | |
| SCHEMBL926116 | 0.82 | PDK2 (0.32) | PDK2 | |
| SCHEMBL935733 | 0.81 | PDK2 (0.38) | PDK2MAPT | |
| SCHEMBL926150 | 0.79 | EPHX2 (0.30) | EPHX2NR1H4 | |
| SCHEMBL18397726 | 0.78 | CYP1A2 (0.35) | EPHX2NR1H4CYP11B2 | |
| SCHEMBL925663 | 0.77 | EPHX2 (0.31) | PDK2EPHX2NR1H4ORAI1 | |
| SCHEMBL28802064 | 0.75 | MCHR1 (0.35) | EPHX2NR1H4MAPT | |
| SCHEMBL27898930 | 0.75 | KDM4E (0.38) | L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242739-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2014-11-12 | — | — | EP | disclosed |
| EP-2242739-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-8304371-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304371-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | BAY CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | BAY CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| WO-2009097992-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | DDT, ACHE, CYP1A2 | PDK2 1748/4885L3MBTL1 1028/4885EPHX2 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.