Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CPA3 | P15088 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259772 | 1.00 | FKBP1A (0.52) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL9260528 | 0.88 | SMN1; SMN2 (0.58) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL7269457 | 0.83 | FKBP1A (0.58) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL7291450 | 0.83 | FKBP1A (0.58) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL7269464 | 0.83 | FKBP1A (0.58) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL5955811 | 0.81 | FKBP1A (0.51) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL5421601 | 0.81 | FKBP1A (0.51) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL5955863 | 0.81 | FKBP1A (0.51) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL9554804 | 0.81 | FKBP1A (0.63) | FKBP1AMMP8SMN1; SMN2RAB9APOLB | |
| SCHEMBL9554813 | 0.81 | FKBP1A (0.63) | FKBP1AMMP8SMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |