Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253587 | 0.86 | MAPT (0.46) | MAPTALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL9256064 | 0.82 | MAPT (0.62) | MAPTALDH1A1PLA2G4BRXRARXRB | |
| SCHEMBL9256061 | 0.82 | MAPT (0.62) | MAPTALDH1A1PLA2G4BRXRARXRB | |
| SCHEMBL1750568 | 0.82 | PLA2G4B (0.63) | ALDH1A1PLA2G4BRXRARXRBNPC1 | |
| SCHEMBL8436025 | 0.81 | MAPK1 (0.67) | MAPTALDH1A1PLA2G4BMAPK1RARB | |
| SCHEMBL8074101 | 0.81 | MAPK1 (0.67) | MAPTALDH1A1PLA2G4BMAPK1RARB | |
| SCHEMBL1749669 | 0.80 | PLA2G4B (0.65) | MAPTALDH1A1PLA2G4BRARBTP53 | |
| Hydrochloric Acid SCHEMBL9812237 | 0.79 | MAPK1 (0.65) | MAPTALDH1A1PLA2G4BMAPK1RARB | |
| Hydrochloric Acid SCHEMBL9812242 | 0.79 | MAPK1 (0.65) | MAPTALDH1A1PLA2G4BMAPK1RARB | |
| SCHEMBL9321559 | 0.79 | PLA2G4B (0.67) | MAPTALDH1A1PLA2G4BRARBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385693-A | Having rapid response and low phase transition temperature | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0357372-B1 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL CO (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5264151-A | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5124070-A | High speed response | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0357372-A2 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |