Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CPA1 | P15085 | 8/20 | 0.51 |
| ▸ | CPA3 | P15088 | 3/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263079 | 1.00 | CYP1A2 (0.58) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL7348126 | 0.81 | CYP1A2 (0.61) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL7348130 | 0.81 | CYP1A2 (0.61) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL7322955 | 0.80 | CYP1A2 (0.66) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL7322967 | 0.80 | CYP1A2 (0.66) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL7322961 | 0.80 | CYP1A2 (0.66) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL8106525 | 0.77 | CYP1A2 (0.79) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL839261 | 0.77 | CYP1A2 (0.79) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL6154166 | 0.77 | CYP1A2 (0.79) | CYP1A2CPA1CPA3FOLH1CPB1 | |
| SCHEMBL839262 | 0.77 | CYP1A2 (0.79) | CYP1A2CPA1CPA3FOLH1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |