Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257063 | 0.79 | HSD17B10 (0.40) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9306122 | 0.72 | HSD17B10 (0.47) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9305128 | 0.72 | CYP2D6 (0.50) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8134231 | 0.71 | HSD17B10 (0.46) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9303584 | 0.70 | CYP2D6 (0.57) | TSHRHSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL9304159 | 0.70 | KDM4E (0.40) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8138785 | 0.69 | HSD17B10 (0.50) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8141253 | 0.69 | HSD17B10 (0.45) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8135773 | 0.69 | CYP2D6 (0.56) | TSHRHSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL9254876 | 0.69 | HSD17B10 (0.43) | TSHRHSD17B10KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428169-A | Antidepressants, treating compulsive disorders, stuttering, trichotillomania | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-5380847-A | Reaction of 1-methylpiperidine-4-hydrazine, ketone and titanium isopropoxide to form hydrazone | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0594001-A1 | Pyrazolo 4,3-c pyridines, a process for their preparation and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | disclosed |
| US-5264576-A | Antiserotonin agents, antidepressants and obsessive-compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |