Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663247 | 0.82 | PARP1 (0.45) | PARP1GRIN1GRIN2AACHEELANE | |
| SCHEMBL3107616 | 0.82 | KMT2A (0.39) | KMT2APARP1ACHEELANEBCHE | |
| SCHEMBL5234447 | 0.81 | PARP1 (0.41) | PARP1GRIN1GRIN2AACHEELANE | |
| SCHEMBL9258621 | 0.78 | GRIN1 (0.36) | KMT2APARP1GRIN1GRIN2AACHE | |
| SCHEMBL30013654 | 0.76 | PARP1 (0.44) | PARP1GRIN1GRIN2AACHEELANE | |
| SCHEMBL3337344 | 0.76 | PARP1 (0.44) | PARP1GRIN1GRIN2AACHEELANE | |
| SCHEMBL7417855 | 0.73 | PARP1 (0.50) | KMT2APARP1GRIN1GRIN2AACHE | |
| SCHEMBL92745 | 0.73 | KMT2A (0.50) | KMT2AACHETDP1 | |
| SCHEMBL15537493 | 0.71 | ALDH1A1 (0.37) | KMT2A | |
| SCHEMBL31140889 | 0.70 | PARP1 (0.46) | PARP1GRIN1GRIN2AACHEELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387585-A | Treating epilepsy, anxiety, sleep disorders, schizophrnia, senile dementia | HOFFMANN-LA ROCHE INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0519307-A2 | Tetracyclic Imidazodiazepines | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-23 | — | — | EP | disclosed |