Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537083 | 0.81 | PDPK1 (0.52) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL5014843 | 0.78 | PDPK1 (0.48) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL5692672 | 0.76 | PDPK1 (0.64) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL10459362 | 0.75 | PDPK1 (0.53) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL610449 | 0.75 | PDPK1 (0.48) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL1951149 | 0.74 | PDPK1 (0.61) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL10448407 | 0.74 | PDPK1 (0.44) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| Hydrochloric Acid SCHEMBL19894001 | 0.73 | PDPK1 (0.47) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL2084670 | 0.70 | PDPK1 (0.43) | PDPK1RAB9AADORA2AADORA1ADRA1A | |
| SCHEMBL8567274 | 0.70 | PDPK1 (0.55) | PDPK1RAB9AADORA2AADORA1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442047-A | Process for preparing isepamicin | SCHERING CORPORATION (US) | 1995-08-15 | — | — | US | claimed |
| EP-0405820-B1 | Improved process for preparing isepamicin | SCHERING CORP (US) | 1994-04-13 | — | — | EP | claimed |
| EP-0478707-A1 | IMPROVED PROCESS FOR PREPARING ISEPAMICIN | SCHERING CORPORATION (US) | 1992-04-08 | — | — | EP | claimed |
| EP-0405820-A2 | Improved process for preparing isepamicin | SCHERING CORPORATION (US) | 1991-01-02 | — | — | EP | claimed |
| WO-1990015810-A2 | IMPROVED PROCESS FOR PREPARING ISEPAMICIN | SCHERING CORPORATION (US) | 1990-12-27 | — | — | WO | claimed |
| EP-0478707-A1 | IMPROVED PROCESS FOR PREPARING ISEPAMICIN | SCHERING CORPORATION (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0405820-A2 | Improved process for preparing isepamicin | SCHERING CORPORATION (US) | 1991-01-02 | — | — | EP | disclosed |
| WO-1990015810-A2 | IMPROVED PROCESS FOR PREPARING ISEPAMICIN | SCHERING CORPORATION (US) | 1990-12-27 | — | — | WO | disclosed |