Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 12/20 | 0.49 |
| ▸ | MMP3 | P08254 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833189 | 0.95 | MMP8 (0.49) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL4844597 | 0.89 | MMP8 (0.44) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL4839633 | 0.89 | MMP8 (0.43) | MMP8MMP3ALDH1A1NPSR1PTGER3 | |
| SCHEMBL4833948 | 0.89 | MMP8 (0.43) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL4845085 | 0.88 | MMP8 (0.42) | MMP8MMP3ALDH1A1NPSR1PTGER3 | |
| SCHEMBL4841463 | 0.87 | MMP8 (0.42) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL4837917 | 0.87 | MMP8 (0.42) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL4841501 | 0.87 | MMP8 (0.42) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL927537 | 0.87 | MMP8 (0.44) | MMP8MMP3ALDH1A1NPSR1MAPT | |
| SCHEMBL926278 | 0.87 | MMP8 (0.44) | MMP8MMP3ALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872021-B2 | LXR receptor modulators | LABORATORIES FOURNIER S.A. (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20070099960-A1 | LXR receptor modulators | LABORATOIRES FOURNIER S.A. (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099960-A1 | LXR receptor modulators | NR1H2, NR1H3, PPARD | MMP8 4719/4885MMP3 4694/4885ALDH1A1 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.