⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637461 | 0.74 | — | — | |
| SCHEMBL2513383 | 0.74 | — | — | |
| SCHEMBL1937136 | 0.74 | — | — | |
| SCHEMBL1935587 | 0.70 | HTR2A (0.31) | — | |
| SCHEMBL1937353 | 0.70 | — | — | |
| SCHEMBL1937099 | 0.69 | — | — | |
| SCHEMBL1935531 | 0.66 | — | — | |
| SCHEMBL8535757 | 0.66 | — | — | |
| SCHEMBL5152191 | 0.64 | SLC6A2 (0.43) | — | |
| SCHEMBL7915921 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420122-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | claimed |
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | claimed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | claimed |
| US-5420122-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0272455-A1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |