Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198463 | 0.82 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3GRM2 | |
| SCHEMBL1858039 | 0.77 | LMNA (0.50) | TAAR1 | |
| SCHEMBL51254 | 0.76 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| SCHEMBL2186411 | 0.76 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| SCHEMBL873444 | 0.76 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| Methane SCHEMBL28820455 | 0.74 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| SCHEMBL183865 | 0.73 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| SCHEMBL989433 | 0.73 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| SCHEMBL14912005 | 0.71 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 | |
| Dimethylamine SCHEMBL28875130 | 0.69 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3GRM2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205202-A | Quaternary carbon center-containing symmetric gem-difluoroolefin derivative and synthesis method thereof | 华南理工大学 | 2020-05-29 | — | — | CN | claimed |
| US-20070208036-A1 | Arylalkanes, arylalkenes and aryl-azaalkanes, pharmaceutical compositions containing these compounds and processes for preparing them | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-09-06 | — | — | US | claimed |
| US-20050113421-A1 | Thiazolidinone, oxazolidinone, and imidazolone derivatives for treating non-inflammatory gastrointestinal tract disorders | DYNOGEN PHARMACEUTICALS, INC. (US) | 2005-05-26 | — | — | US | claimed |
| EP-0912552-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATES AS DOPAMINE D4 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2004-04-21 | — | — | EP | claimed |
| CN-1134431-C | 2,4-diaminopyrimidine derivatives as dopamine D4 receptor antagonists | ��˹��ŵ�� | 2004-01-14 | — | — | CN | claimed |
| US-6395742-B1 | PSYCHOLOGICAL DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-05-28 | — | — | US | claimed |
| CN-1218466-A | 2,4-diaminopyrimidine derivatives as dopamine d4 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 1999-06-02 | — | — | CN | claimed |
| EP-0912552-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATES AS DOPAMINE D4 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-05-06 | — | — | EP | claimed |
| WO-1997043279-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATES AS DOPAMINE D4 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-20 | — | — | WO | claimed |
| EP-0785923-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-07-30 | — | — | EP | claimed |
| WO-1996011909-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-25 | — | — | WO | claimed |
| CN-111205202-A | Quaternary carbon center-containing symmetric gem-difluoroolefin derivative and synthesis method thereof | 华南理工大学 | 2020-05-29 | — | — | CN | disclosed |
| CN-101918387-B | Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same | SUMITOMO CHEMICAL CO | 2013-07-24 | — | — | CN | disclosed |
| CN-101918387-A | Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same | SUMITOMO CHEMICAL CO | 2010-12-15 | — | — | CN | disclosed |
| CN-100519525-C | Aromatic sulfones and their medical use | GLAXO GROUP LTD (GB) | 2009-07-29 | — | — | CN | disclosed |
| US-6147100-A | ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0976748-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1218466-A | 2,4-diaminopyrimidine derivatives as dopamine d4 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 1999-06-02 | — | — | CN | disclosed |
| EP-0912552-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATES AS DOPAMINE D4 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043279-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATES AS DOPAMINE D4 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208036-A1 | Arylalkanes, arylalkenes and aryl-azaalkanes, pharmaceutical compositions containing these compounds and processes for preparing them | ARRB1, NPY1R, ADRB3 | SLC6A2 723/4885SLC6A4 811/4885SLC6A3 420/4885 |
| US-20050113421-A1 | Thiazolidinone, oxazolidinone, and imidazolone derivatives for treating non-inflammatory gastrointestinal tract disorders | TRPV2, RYR2, VDAC2 | SLC6A2 2788/4885SLC6A4 2372/4885SLC6A3 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.