Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 9/20 | 0.71 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.71 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.71 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | THPO | P40225 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301606 | 1.00 | CACNA1C (0.71) | CACNA1CCACNA1FCACNA1DCACNA1SCACNA1B | |
| SCHEMBL8298083 | 1.00 | CACNA1C (0.71) | CACNA1CCACNA1FCACNA1DCACNA1SCACNA1B | |
| SCHEMBL8298086 | 1.00 | CACNA1C (0.71) | CACNA1CCACNA1FCACNA1DCACNA1SCACNA1B | |
| SCHEMBL7481538 | 0.96 | CACNA1F (0.77) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10987979 | 0.94 | CACNA1F (0.72) | CACNA1CCACNA1FCACNA1DCACNA1SCACNA1B | |
| SCHEMBL8523670 | 0.93 | CACNA1F (0.83) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10747346 | 0.92 | CACNA1F (0.71) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL9154274 | 0.92 | MEN1 (0.76) | CACNA1CCACNA1FCACNA1DCACNA1SCACNA1B | |
| SCHEMBL9583587 | 0.92 | HIF1A (0.76) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL29684193 | 0.92 | MEN1 (0.76) | CACNA1CCACNA1FCACNA1DCACNA1SCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395941-A | Optically active 1,4-hydropyridine compounds | MERCIAN CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |