Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | THPO | P40225 | 2/20 | 0.76 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.74 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.74 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.74 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | MLNR | O43193 | 1/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.71 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684193 | 1.00 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7481538 | 0.96 | CACNA1F (0.77) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9583587 | 0.94 | HIF1A (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30876841 | 0.94 | HIF1A (0.76) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| Methane SCHEMBL29206052 | 0.93 | HIF1A (0.75) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8523670 | 0.93 | CACNA1F (0.83) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8298083 | 0.92 | CACNA1C (0.71) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8298086 | 0.92 | CACNA1C (0.71) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8301606 | 0.92 | CACNA1C (0.71) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10747346 | 0.92 | CACNA1F (0.71) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002343-A1 | COMPOUNDS HAVING INHIBITORY EFFECT ON MITOCHONDRIAL HYPERFISSION | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2024-01-04 | — | — | US | disclosed |
| EP-4252843-A1 | COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS | Kyushu University, National University Corporation (JP) | 2023-10-04 | — | — | EP | disclosed |
| EP-4252843-A1 | COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS | Kyushu University, National University Corporation (JP) | 2023-10-04 | — | — | EP | disclosed |
| US-5403849-A | Treatment of central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| US-4483985-A | ALKALINE HYDROLYSIS OF ESTER GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-20 | — | — | US | disclosed |
| US-4285955-A | CARDIOTONIC, HYPOTENSIVE, AND ANTISPASMOTIC AGENTS; VASODILATION | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002343-A1 | COMPOUNDS HAVING INHIBITORY EFFECT ON MITOCHONDRIAL HYPERFISSION | CS, FH, CYC1 | MEN1 3180/4885KMT2A 3608/4885CYP1A2 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.