SCHEMBL9264396

SCHEMBL9264396

Cc1[nH]c(C)c(-c2cccc(Oc3ccc(Cl)cc3)c2)c(=O)c1Br

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.57
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
BRD4 O60885 1/20 0.37
MAPK13 O15264 1/20 0.37
GCGR P47871 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9261054 0.87 SLC2A1 (0.74) SLC2A1MEN1CYP1A2KMT2ABRD4
SCHEMBL9268614 0.82 SLC2A1 (0.56) SLC2A1CYP1A2BRD4
SCHEMBL9272554 0.80 SLC2A1 (0.56) SLC2A1MEN1CYP1A2KMT2ABRD4
SCHEMBL9265388 0.80 SLC2A1 (0.50) SLC2A1KDM4EMEN1CYP1A2CYP2D6
SCHEMBL9263799 0.78 SLC2A1 (0.59) SLC2A1KDM4EMEN1KMT2AHSD17B10
SCHEMBL25849454 0.78 SLC2A1 (0.49) SLC2A1KDM4EMEN1CYP1A2CYP2D6
SCHEMBL9268107 0.78 SLC2A1 (0.57) SLC2A1KDM4ENR1H2NR1H3BRD4
SCHEMBL9261485 0.78 SLC2A1 (0.46) SLC2A1NR1H2NR1H3MAPK14
SCHEMBL9267776 0.77 SLC2A1 (0.57) SLC2A1KDM4EMEN1KMT2AHSD17B10
SCHEMBL9268714 0.74 SLC2A1 (0.55) SLC2A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403934-A Heterocyclic compounds BURROUGHS WELLCOME CO. (US) 1995-04-04 US disclosed