Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 14/20 | 0.45 |
| ▸ | TYMP | P19971 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989131 | 1.00 | KDM4E (0.47) | KDM4EPKMGPR84TYMPSLC2A1 | |
| SCHEMBL12989313 | 1.00 | KDM4E (0.47) | KDM4EPKMGPR84TYMPSLC2A1 | |
| SCHEMBL5386151 | 0.78 | KDM4E (0.44) | KDM4EPKMGPR84CTSVCTSL | |
| SCHEMBL12603450 | 0.76 | TYR (0.42) | KDM4EPKMGPR84 | |
| SCHEMBL3141357 | 0.73 | KDM4E (0.41) | KDM4EPKMGPR84 | |
| SCHEMBL15818859 | 0.73 | KDM4E (0.37) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL15865150 | 0.72 | KDM4E (0.36) | KDM4EPKM | |
| SCHEMBL3406838 | 0.70 | KDM4E (0.43) | KDM4EPKMGPR84 | |
| SCHEMBL22402758 | 0.69 | KDM4E (0.41) | KDM4EPKMTYMP | |
| SCHEMBL12988968 | 0.69 | SLC2A1 (0.47) | KDM4EGPR84TYMPSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |