Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762210 | 0.88 | KDM4E (0.41) | KDM4EPKMOXER1GPR84 | |
| SCHEMBL15570393 | 0.80 | HCAR2 (0.40) | KDM4EHCAR2 | |
| SCHEMBL23147412 | 0.76 | ALDH1A1 (0.40) | KDM4EHCAR2 | |
| SCHEMBL9454685 | 0.74 | ALDH1A1 (0.55) | KDM4E | |
| SCHEMBL10468545 | 0.73 | GPR84 (0.45) | KDM4EBIDMCL1BCL2L1BAK1 | |
| SCHEMBL10686284 | 0.72 | NOTUM (0.45) | KDM4EHCAR2 | |
| SCHEMBL12989313 | 0.70 | KDM4E (0.47) | KDM4EPKMGPR84 | |
| SCHEMBL9264403 | 0.70 | KDM4E (0.47) | KDM4EPKMGPR84 | |
| SCHEMBL12989131 | 0.70 | KDM4E (0.47) | KDM4EPKMGPR84 | |
| SCHEMBL15569668 | 0.69 | ALDH1A1 (0.36) | KDM4EPKMHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261211-A1 | 1,4-dihydropyridine derivatives and their uses | Université de Lille 2 Droit et Santé (FR) | 2010-12-15 | — | — | EP | disclosed |