Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962712 | 0.87 | FUCA1 (0.58) | TACR1FUCA1S1PR1S1PR5GAA | |
| SCHEMBL9635245 | 0.86 | POLB (0.43) | TACR1KDM4EMEN1KMT2AHRH3 | |
| SCHEMBL7225576 | 0.82 | MC4R (0.53) | FUCA1S1PR1S1PR5GAASIGMAR1 | |
| SCHEMBL20008958 | 0.82 | GRIN2B (0.51) | KDM4EMEN1KMT2AFUCA1HRH3 | |
| SCHEMBL19518531 | 0.80 | FUCA1 (0.55) | FUCA1S1PR1S1PR5GAASIGMAR1 | |
| SCHEMBL20417932 | 0.80 | FUCA1 (0.55) | FUCA1S1PR1S1PR5GAASIGMAR1 | |
| SCHEMBL30875889 | 0.80 | FUCA1 (0.55) | FUCA1S1PR1S1PR5GAASIGMAR1 | |
| SCHEMBL1514852 | 0.80 | FUCA1 (0.55) | FUCA1S1PR1S1PR5GAASIGMAR1 | |
| SCHEMBL18339637 | 0.80 | FUCA1 (0.55) | TACR1FUCA1S1PR1S1PR5GAA | |
| SCHEMBL31327374 | 0.80 | FUCA1 (0.55) | TACR1FUCA1S1PR1S1PR5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468858-A | Sudden death syndrome | THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY PHYSICAL SCIENCES (US) | 1995-11-21 | — | — | US | disclosed |
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| WO-1991007405-A1 | SALTS OF 3-AZABICYCLO[3.3.1]NONANES AS ANTIARRHYTHMIC AGENTS, AND PRECURSORS THEREOF | THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1991-05-30 | — | — | WO | disclosed |