Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265205 | 0.86 | TACR1 (0.47) | S1PR5TACR1KDM4EALDH1A1MEN1 | |
| SCHEMBL9636794 | 0.80 | CXCR3 (0.43) | POLBS1PR5TACR1KDM4EALDH1A1 | |
| SCHEMBL9635246 | 0.78 | KDM4E (0.52) | S1PR5KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31518800 | 0.77 | TSHR (0.42) | ALDH1A1GRM2P2RX3 | |
| SCHEMBL9261212 | 0.76 | MAPT (0.33) | ALDH1A1 | |
| SCHEMBL14983598 | 0.74 | SIGMAR1 (0.61) | POLBKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23978589 | 0.73 | SRD5A1 (0.45) | — | |
| SCHEMBL2962712 | 0.71 | FUCA1 (0.58) | S1PR5TACR1SIGMAR1GAA | |
| SCHEMBL11234409 | 0.69 | CARM1 (0.48) | TACR1 | |
| SCHEMBL21145988 | 0.68 | PIK3CD (0.31) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991007405-A1 | SALTS OF 3-AZABICYCLO[3.3.1]NONANES AS ANTIARRHYTHMIC AGENTS, AND PRECURSORS THEREOF | THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1991-05-30 | — | — | WO | disclosed |