Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271155 | 0.80 | CYP3A4 (0.50) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL6912133 | 0.78 | CYP3A4 (0.54) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL5715985 | 0.78 | KMT2A (0.48) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL8115316 | 0.78 | MEN1 (0.44) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL31733931 | 0.77 | CYP3A4 (0.47) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL3700781 | 0.75 | MEN1 (0.50) | KMT2ACYP3A4MEN1GLAALDH1A1 | |
| Benzene SCHEMBL27508653 | 0.74 | CYP3A4 (0.48) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL30302271 | 0.74 | CYP3A4 (0.48) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL2316707 | 0.74 | CYP3A4 (0.48) | KMT2ACYP3A4MEN1GLATDP1 | |
| SCHEMBL9269514 | 0.74 | CYP3A4 (0.44) | KMT2ACYP3A4MEN1GLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443970-A | SEPARATION OF ISOMERS IN A MIXTURE BY SELECTIVE REACTION | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| EP-0604483-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993006235-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES | ZENECA LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |